Ernest Beutler: his life and contribution to medical science

Erythrocyte Glutathione Reductase By ERNEST BEUTLER AND MARY

By ERNEST BEUTLER AND MARY K. Y. Yu m T HE EXACT ROLE of reduced glutathione ( OSH ) in the economy of the red blood cell remains to be defined. Drug-induced hemolytic anemia due to glucose-6-phosphate dehydrogenase deficiency is associated with lowt and with unstable2 0S1-I. Yet, a condition has been described in which red cell glutathione is virtually absent with only mild hemolysis being obs...

Ernest William Hey Groves and His Contributions to Orthopaedic Surgery

Ernest William Hey Groves was the son of an English civil engineer and was born in India on 20th June 1872. At the age of three, when his father retired, the family settled in Bristol. He inherited an aptitude for mechanics and took a B.Sc. in engineering. In London, while pursuing his science course, he saw an advertisement for a scholarship at St. Bartholomew's Hospital, London, which include...

Humphry Davy: his life, works, and contribution to anesthesiology.

H ISTORY offers us a tool to avoid the condemnation George Santayana (1863–1952) envisioned for those who forget the past. In studying the history of anesthesia, and in particular the singular events that brought anesthesia into the consciousness of the world in Boston in 1845 and 1846, we find much to admire, but even more that we might hope not to repeat. The first public demonstrations of an...

Enrico Drioli and His Life Time Love Affair with Membrane Science

ERNEST BEUTLER Table 1 . Results of Studies of Sickle Hemoglobin Viscosity at a Fixed Per

T HE RELATIONSHIP between oxygen tension and the sickling phenomenon has been recognized for over 45 years’ and has become central to our thinking about sickle cell disease. It has been emphasized that sickling of red cells depends to a large degree upon the absolute concentration of reduced sickle hemoglobin.2 In the past two decades many therapeutic strategies have been explored in the manage...